HCID 53844855, compound → 3-acetoxy-3-(N-acetylisopropylaminomethyl)-7-amino-3,4-dihydro-2H-1,5-benzodioxepin

HRID 267774Notes

Reaction equation

HRID 267774 reaction equation
[C:1]([O:4][C:5]1([CH2:19][N:20]([CH:24]([CH3:26])[CH3:25])[C:21](=[O:23])[CH3:22])[CH2:11][O:10][C:9]2[CH:12]=[CH:13][C:14]([N+:16]([O-])=O)=[CH:15][C:8]=2[O:7][CH2:6]1)(=[O:3])[CH3:2].[H][H]>C(OCC)(=O)C.[Pt]>[C:1]([O:4][C:5]1([CH2:19][N:20]([CH:24]([CH3:26])[CH3:25])[C:21](=[O:23])[CH3:22])[CH2:11][O:10][C:9]2[CH:12]=[CH:13][C:14]([NH2:16])=[CH:15][C:8]=2[O:7][CH2:6]1)(=[O:3])[CH3:2]

Participants

5

Reactant 2

HCID 53844855HCID 53844855, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 540731773-acetoxy-3-(N-acetylisopropylaminomethyl)-7-amino-3,4-dihydro-2H-1,5-benzodioxepin

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

The 3-acetoxy-3-(N-acetylisopropylaminomethyl)-7-nitro-3,4-dihydro-2H-1,5-benzodioxepin when dissolved in ethyl acetate is reduced at low pressure over platinum with hydrogen to give 3-acetoxy-3-(N-acetylisopropylaminomethyl)-7-amino-3,4-dihydro-2H-1,5-benzodioxepin.

Sources & evidence

ORD record
ord-1be76147e9bd4e39a51a1b1a9e1a1b39
Source dataset
uspto-grants-1976_03
Patent number
US03944560

Reaction notes

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