Hydrochloric Acid → HCID 68144523, compound

HRID 268174Notes

Reaction equation

HRID 268174 reaction equation
B.N1CCC[C@H]1C(O)=O.Cl.[Cl:11][C:12]1[C:22]2[N:21]([CH3:23])[C:20](=[O:24])[CH:19]3[CH2:25][CH2:26][CH2:27][N:18]3[C:17](=O)[C:16]=2[CH:15]=[C:14]([O:29][CH3:30])[CH:13]=1>O1CCCC1>[Cl:11][C:12]1[C:22]2[N:21]([CH3:23])[C:20](=[O:24])[CH:19]3[CH2:25][CH2:26][CH2:27][N:18]3[CH2:17][C:16]=2[CH:15]=[C:14]([O:29][CH3:30])[CH:13]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 6331BoraneHCID 145742L-ProlineHCID 86733177HCID 86733177, compound

Product 1

HCID 68144523HCID 68144523, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

This compound is obtained when a mixture of 1M borane in tetrahydrofuran and 9-chloro-1,2,3,11 a-tetrahydro-7-methoxy-10-methyl-5 H-pyrrolo[2,1-c] [1,4] benzodiazepin-5,11 -(10H)-dione (prepared from proline and 3-chloro-5 -methoxy-N-(methylisatoic anhydride as described in Example 1) are allowed to react as described in Example 1.

Workup

  1. customThis compound is obtained when
  2. customto react

Sources & evidence

ORD record
ord-645719505fd44e6188b4bf7fab3b62f8
Source dataset
uspto-grants-1976_03
Patent number
US03947408

Reaction notes

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