Benzenamine, 3-(methylthio)- → HCID 178503176, compound

HRID 268256Notes

Reaction equation

HRID 268256 reaction equation
[ClH:1].[NH:2]([C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]3[N:21]=[CH:20][NH:19][C:17]3=2)[N:12]=[C:11]([CH3:22])[CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:23][S:24]C1C=C(C=CC=1)N>CN(C)C=O>[ClH:1].[CH3:23][S:24][C:5]1[CH:4]=[C:3]([CH:8]=[CH:7][CH:6]=1)[NH:2][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]3[N:21]=[CH:20][NH:19][C:17]3=2)[N:12]=[C:11]([CH3:22])[CH:10]=1

Participants

4

Reactant 2

HCID 15693Benzenamine, 3-(methylthio)-HCID 178428198HCID 178428198, compound

Product 1

HCID 178503176HCID 178503176, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 21.7 g. (0.1 m.) of the compound of Example I, C., 13.9 g. (0.1 m.) of 3-methylmercaptoaniline and 250 ml. of dimethylformamide was refluxed overnight with stirring. It was chilled, filtered, washed with ether and air-dried to give 29 g. m.p. 310°-313°C.

Workup

  1. additionA mixture of 21.7 g
  2. temperatureIt was chilled
  3. filtrationfiltered
  4. washwashed with ether
  5. customair-dried
  6. customto give 29 g

Sources & evidence

ORD record
ord-7a207709f5e542a1a6bcd62f146b7786
Source dataset
uspto-grants-1976_03
Patent number
US03947434

Reaction notes

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