反应详情

A mixture of 2.0 g. (6.4 mmol.) of 3-(4-hydroxybenzoyl)-2-phenylbenzofuran, 1.3 g. (6.4 mmol.) of 3-di-n-butylaminopropyl chloride and 4.0 g. (0.04 mol.) of anhydrous potassium carbonate in 20 ml. of dry 2-butanone is refluxed for 18 hours. The reaction is cooled, water and ether are added and the layers are separated. The organic phase is extracted with 10% aqueous sodium hydroxide and the aqueous layers are combined and extracted again with water. The combined ether extracts are concentrated under reduced pressure to give the title compound.

1. additionA mixture of 2.0 g
2. temperatureThe reaction is cooled
3. customthe layers are separated
4. extractionThe organic phase is extracted with 10% aqueous sodium hydroxide
5. extractionextracted again with water
6. concentrationThe combined ether extracts are concentrated under reduced pressure