Hydrochloric Acid → N-[5-methanesulfonyl-4-(4-methanesulfonyl-3-pentafluorosulfanylphenoxy)-2-methylbenzoyl]guanidine, hydrochloride

HRID 269421Notes

Reaction equation

HRID 269421 reaction equation
[CH3:1][S:2]([C:5]1[C:6]([O:18][C:19]2[CH:24]=[CH:23][C:22]([S:25]([CH3:28])(=[O:27])=[O:26])=[C:21]([S:29]([F:34])([F:33])([F:32])([F:31])[F:30])[CH:20]=2)=[CH:7][C:8]([CH3:17])=[C:9]([CH:16]=1)[C:10]([NH:12][C:13]([NH2:15])=[NH:14])=[O:11])(=[O:4])=[O:3].[ClH:35]>>[ClH:35].[CH3:1][S:2]([C:5]1[C:6]([O:18][C:19]2[CH:24]=[CH:23][C:22]([S:25]([CH3:28])(=[O:27])=[O:26])=[C:21]([S:29]([F:32])([F:34])([F:33])([F:30])[F:31])[CH:20]=2)=[CH:7][C:8]([CH3:17])=[C:9]([CH:16]=1)[C:10]([NH:12][C:13]([NH2:15])=[NH:14])=[O:11])(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178428844HCID 178428844, compound

Product 1

HCID 178428845N-[5-methanesulfonyl-4-(4-methanesulfonyl-3-pentafluorosulfanylphenoxy)-2-methylbenzoyl]guanidine, hydrochloride

Procedure

400 mg of N-[5-methanesulfonyl-4-(4-methanesulfonyl-3-pentafluorosulfanylphenoxy)-2-methylbenzoyl]guanidine were dissolved in dilute aqueous HCl solution and then the volatiles were removed in vacuo. The residue was recrystallized from water to result in 200 mg of a pale gray solid, mp 275° C.

Workup

  1. customthe volatiles were removed in vacuo
  2. customThe residue was recrystallized from water

Sources & evidence

ORD record
ord-c8b67a8e58ba454eb255bef2afecc3f3
Source dataset
uspto-grants-2008_11
Patent number
US07446225B2

Reaction notes

Loading…