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HRID269827

反应详情

EQUATION

反应方程式

HRID 269827 的结构方程式

REACTANTS

反应物

4
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：O=[N+]([O-])c1ccc(I)cc1
HCID12495

Benzene, 1-iodo-4-nitro-

C6H4INO2

结构：[Ca+2].[Cl-].[Cl-]
HCID5284359

未命名化合物

结构：CC(C)(C)OC(=O)N1CCNC(=O)CC1
HCID22617736

tert-Butyl 5-oxo-1,4-diazepane-1-carboxylate

C10H18N2O3

PRODUCTS

生成物

1
结构：Nc1ccc(N2CCN(C(=O)OCc3ccccc3)CCC2=O)cc1
HCID23071585

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

4
结构：[Cu]
催化剂HCID23978

Copper

Cu

结构：[Zn]
催化剂HCID23994

Zinc

Zn

结构：CCO
溶剂HCID702

Ethanol

C2H6O

结构：Clc1ccccc1Cl
溶剂HCID7239

1,2-Dichlorobenzene

C6H4Cl2

PROCEDURE

实验过程

4-Iodonitrobenzene and tert-butyl 5-oxo-[1,4]diazepan-1-carboxylate were allowed to undergo the reaction in 1,2-dichlorobenzene in the presence of copper powder and potassium carbonate, and then the nitro group was reduced in ethanol using zinc powder and calcium chloride to obtain benzyl 4-(4-aminophenyl)-5-oxo-1,4-diazepan-1-carboxylate. ESI: 340.