1,1-Bis(methylthio)-2-nitroethylene → 1-Nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethylene

HRID 27123Notes

Reaction equation

HRID 27123 reaction equation
Br[C:2]1[NH:6][CH:5]=[N:4][C:3]=1[CH2:7][CH2:8][CH2:9][CH2:10][NH2:11].[N+:12]([CH:15]=[C:16](SC)[S:17][CH3:18])([O-:14])=[O:13]>C(O)(C)C>[N+:12]([CH:15]=[C:16]([S:17][CH3:18])[NH:11][CH2:10][CH2:9][CH2:8][CH2:7][C:3]1[N:4]=[CH:5][NH:6][CH:2]=1)([O-:14])=[O:13]

Participants

4

Reactant 2

HCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 178510963HCID 178510963, compound

Product 1

HCID 1785038211-Nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethylene

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Reaction of 5-bromo-4(4-aminobutyl)imidazole with 1-nitro-2,2-bis-methylthioethylene in the procedure of Example 8(i) yields 1-nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethylene, m.p. 157°-158°, (from isopropanol).

Sources & evidence

ORD record
ord-dc51b310f2da43c4a27864ec87cff893
Source dataset
uspto-grants-1980_09
Patent number
US04220652

Reaction notes

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