Isopropylamine → HCID 58772830, compound

HRID 271449Notes

Reaction equation

HRID 271449 reaction equation
Cl[C:2]1[N:7]2[C:8](=[O:11])[NH:9][N:10]=[C:6]2[C:5]([C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=2)=[C:4]([C:19]2[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=2)[N:3]=1.[CH:26]([NH2:29])([CH3:28])[CH3:27]>C1COCC1>[Cl:25][C:22]1[CH:23]=[CH:24][C:19]([C:4]2[N:3]=[C:2]([NH:29][CH:26]([CH3:28])[CH3:27])[N:7]3[C:8](=[O:11])[NH:9][N:10]=[C:6]3[C:5]=2[C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=2)=[CH:20][CH:21]=1

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 587728405-chloro-7,8-bis(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one

Product 1

HCID 58772830HCID 58772830, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a stirring solution of 5-chloro-7,8-bis(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one (39 mg, 0.10 mmol) in 1 mL THF, was added isopropylamine (18 mg, 0.30 mmol). The reaction mixture was stirred at room temperature for 1 h and then concentrated under reduced pressure. The resulting crude title compound was used in the next step without further purification.

Workup

  1. concentrationconcentrated under reduced pressure
  2. customThe resulting crude title compound was used in the next step without further purification

Sources & evidence

ORD record
ord-fe6ed3745cb84b19b8d45685c6afdf0d
Source dataset
uspto-grants-2008_11
Patent number
US07452892B2

Reaction notes

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