Hydrochloric Acid → 3,3,3-Tris(4-vinylphenyl)propionic acid

HRID 272084Notes

Reaction equation

HRID 272084 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]([C:23]2[CH:28]=[CH:27][C:26]([CH:29]=[CH2:30])=[CH:25][CH:24]=2)([C:15]2[CH:20]=[CH:19][C:18]([CH:21]=[CH2:22])=[CH:17][CH:16]=2)[CH2:10][C:11]([O:13]C)=[O:12])=[CH:5][CH:4]=1)=[CH2:2].[OH-].[Li+].Cl>O1CCOCC1>[CH:29]([C:26]1[CH:25]=[CH:24][C:23]([C:9]([C:6]2[CH:5]=[CH:4][C:3]([CH:1]=[CH2:2])=[CH:8][CH:7]=2)([C:15]2[CH:20]=[CH:19][C:18]([CH:21]=[CH2:22])=[CH:17][CH:16]=2)[CH2:10][C:11]([OH:13])=[O:12])=[CH:28][CH:27]=1)=[CH2:30]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3939Lithium HydroxideHCID 22647215Methyl 3,3,3-tris(4-vinylphenyl)propionate

Product 1

HCID 226473893,3,3-Tris(4-vinylphenyl)propionic acid

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Conditions

Temperature
90 °C

Procedure

Fifty-four (54) mg of methyl 3,3,3-tris(4-vinylphenyl)-propionate was suspended in 0.5 ml of dioxane, and to the suspension 0.5 ml of 4N aqueous lithium hydroxide solution was added at room temperature, followed by 17 hours' stirring at 90° C. under heating. The reaction liquid was made acidic by addition of 1N hydrochloric acid, extracted with chloroform and dried over anhydrous sodium sulfate. Distilling the solvent off under reduced pressure, 52.5 mg of the title compound was obtained.

Workup

  1. temperatureunder heating
  2. customThe reaction liquid
  3. extractionextracted with chloroform
  4. dry with materialdried over anhydrous sodium sulfate
  5. distillationDistilling the solvent off under reduced pressure

Sources & evidence

ORD record
ord-535d0ea3672041d9a8a7efe14f219fa0
Source dataset
uspto-grants-2008_11
Patent number
US07452908B2

Reaction notes

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