Tert-Butylamine → HCID 3378586, compound

HRID 272559Notes

Reaction equation

[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[CH:2]=[CH2:3].[C:8]([NH2:12])([CH3:11])([CH3:10])[CH3:9]>>[CH2:6]([O:5][C:1](=[O:4])[CH2:2][CH2:3][N:12]([C:8]([CH3:11])([CH3:10])[CH3:9])[CH2:3][CH2:2][C:1]([O:5][CH2:6][CH3:7])=[O:4])[CH3:7]

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 8821Ethyl Acrylate

Product 1

HCID 3378586HCID 3378586, compoundYield 14.5%

Procedure

A mixture of ethyl acrylate (0.735 mol) and tert-butyl amine (0.210 mol) was refluxed for 6 days. The crude mixture was purified by fractionated distillation in vacuo (5 mbar). One fraction was collected (boiling point: 120° C. at 5 mbar), yielding to 8.3 g of the desired product as a light yellow oil. MS (m/e): 274.4 (MH+, 100%).

Workup

temperaturewas refluxed for 6 days
distillationThe crude mixture was purified by fractionated distillation in vacuo (5 mbar)
customOne fraction was collected (boiling point: 120° C. at 5 mbar)

Sources & evidence

ORD record: ord-2c4667ee465f4649b7c4323aaa799711
Source dataset: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07456174B2

Reaction notes

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