反应详情

Thiomorpholine (5 g, 49 mmol), acetone (15 ml, 3 vol), 5M NaOH solution (11.8 ml) and 1-bromo-3-chloropropane (11.6 g, 73.5 mmol, 1.5 eq.) were reacted together according to general procedure A to give the title compound (8.5 g, 96%) as a pale yellow oil.