HC Yellow no. 13 → 2-[[2-Amino-4-(trifluoromethyl)phenyl]amino]ethanol

HRID 273363Notes

Reaction equation

HRID 273363 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:7]=[CH:6][C:5]=1[NH:14][CH2:15][CH2:16][OH:17])([O-])=O>C1COCC1>[NH2:1][C:4]1[CH:9]=[C:8]([C:10]([F:12])([F:13])[F:11])[CH:7]=[CH:6][C:5]=1[NH:14][CH2:15][CH2:16][OH:17]

Participants

3

Reactant 1

HCID 2799157HC Yellow no. 13

Product 1

HCID 217101722-[[2-Amino-4-(trifluoromethyl)phenyl]amino]ethanol

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

2-{[2-nitro-4-(trifluoromethyl)phenyl]amino}ethanol (3.05 g, 12 mmol) was dissolved in THF (10 ml) and hydrogenated at 70 psi. After the removal of catalyst the product was obtained by evaporating the solvent and used for the next step (2.70 g, 100%).

Workup

  1. customAfter the removal of catalyst the product
  2. customwas obtained
  3. customby evaporating the solvent

Sources & evidence

ORD record
ord-6a571cd67a9a4531aaa351bc25da194a
Source dataset
uspto-grants-2008_11
Patent number
US07456293B2

Reaction notes

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