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HRID273560

反应详情

EQUATION

反应方程式

HRID 273560 的结构方程式

REACTANTS

反应物

2
结构：Cn1ccnc1CBr
HCID23043578

2-(Bromomethyl)-1-methyl-1H-imidazole

C5H7BrN2

结构：CC(C)(C)OC(=O)N1CCN(c2ccc(NC(=O)c3ccc(-c4ccc(Cl)cc4)o3)cc2)CC1
HCID168301698

未命名化合物

PRODUCTS

生成物

2
结构：Cn1ccnc1CN(C(=O)c1ccc(-c2ccc(Cl)cc2)o1)c1ccc(N2CCNCC2)cc1
HCID70687522

未命名化合物

收率 120%
结构：CC(C)(C)OC(=O)N1CCN(c2ccc(NC(=O)c3ccc(-c4ccc(Cl)cc4)o3)cc2)CC1
HCID168301698

未命名化合物

2 次

AUXILIARIES

试剂、催化剂与溶剂

4
结构：O=S(=O)(O)O
试剂HCID1118

Sulfuric acid

H2O4S

结构：CCN=P(N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C
试剂HCID3393106

Phosphazene base P2-Et

C12H35N7P2

结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

3 次

结构：COCCOCCOC
溶剂HCID8150

Diethylene glycol dimethyl ether

C6H14O3

CONDITIONS

反应条件

温度
23 °C

WORKUP

后处理

  1. additionquenched by addition of saturated aqueous NaHCO3 (2 uL) and diluted with water (1 uL) and DMSO (2 uL)
  2. additionquenched by addition of saturated aqueous NaHCO3 (2 uL) and diluted with water (1 uL) and DMSO (2 uL)
  3. additionquenched by addition of saturated aqueous NaHCO3 (2 uL) and diluted with water (1 uL) and DMSO (2 uL)
  4. additionThe reactions were further diluted to 10 mM using DMSO.