反应详情

A solution of 2-bromoacetylnaphthalene (7.00 g) and tetra-n-butyl ammonium bromide (0.905 g) in 1,2-dichloroethane (226 ml) was refluxed for 3.5 hours, evaporated in vacuo and extracted with dichloromethane. The extract was washed with brine, dried over magnesium sulfate, and evaporated in vacuo. The residue was washed with n-hexane to afford 2-chloroacetylnaphthalene (5.43 g) as a yellow powder.

1. customevaporated in vacuo
2. extractionextracted with dichloromethane
3. washThe extract was washed with brine
4. dry with materialdried over magnesium sulfate
5. customevaporated in vacuo
6. washThe residue was washed with n-hexane