Water → HCID 15217703, compound

HRID 274197Notes

Reaction equation

HRID 274197 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH:10]1[C:23]2[CH:22]=[C:21]([N:24]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:20]([O:37][CH3:38])=[CH:19][C:18]=2[O:17][C:16]2[C:11]1=[CH:12][CH:13]=[C:14]([N:39]([CH2:42][CH3:43])[CH2:40][CH3:41])[CH:15]=2)([OH:3])=[O:2].[C:44](=O)([O-])[O-].[K+].[K+].S(OC)(OC)(=O)=O.O>CN(C)C(=O)C>[CH3:44][O:2][C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH:10]1[C:23]2[CH:22]=[C:21]([N:24]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=3)[C:20]([O:37][CH3:38])=[CH:19][C:18]=2[O:17][C:16]2[C:11]1=[CH:12][CH:13]=[C:14]([N:39]([CH2:40][CH3:41])[CH2:42][CH3:43])[CH:15]=2)=[O:3]

Participants

6

Reactant 4

HCID 962WaterHCID 6497Dimethyl SulfateHCID 11430Potassium CarbonateHCID 15217702HCID 15217702, compound

Product 1

HCID 15217703HCID 15217703, compound

Reagents, catalysts & solvents 1

HCID 31374DimethylacetamideSolvent

Procedure

The carboxylic acid thus obtained and 10 parts of potassium carbonate were mixed in 200 cc of N,N-dimethylacetamide, to which 6.5 parts of dimethyl sulfate was added dropwise at 45° C. followed by stirring at the same temperature for one hour. The resulting reaction mixture was poured into 2 λ of water. Then, the deposited crystals were filtered off and recrystallized with methanol-ethylacetate to obtain 25.7 parts of 9- ( 2-methoxycarbonylphenyl ) -2-diphenylamino-3-methoxy-6-diethylaminoxanthene having a melting point of 117° to 119° C.

Workup

  1. additionwas added dropwise at 45° C.
  2. customThe resulting reaction mixture
  3. filtrationThen, the deposited crystals were filtered off
  4. customrecrystallized with methanol-ethylacetate

Sources & evidence

ORD record
ord-f9e0f4a5efef4c2bbcbee6cfe39f0447
Source dataset
uspto-grants-1995_02
Patent number
US05389489

Reaction notes

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