2-Chloropyridine → HCID 15764889, compound

HRID 274355Notes

Reaction equation

HRID 274355 reaction equation
[CH3:1][CH:2]([O:6][C:7]1[CH:16]=[CH:15][C:10]([O:11][CH2:12][CH2:13][OH:14])=[CH:9][CH:8]=1)[CH2:3][CH2:4][CH3:5].[H-].[Na+].Cl[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1>CN(C=O)C>[CH3:1][CH:2]([O:6][C:7]1[CH:8]=[CH:9][C:10]([O:11][CH2:12][CH2:13][O:14][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=2)=[CH:15][CH:16]=1)[CH2:3][CH2:4][CH3:5]

Participants

5

Reactant 3

HCID 79772-ChloropyridineHCID 24758Sodium hydrideHCID 15764888HCID 15764888, compound

Product 1

HCID 15764889HCID 15764889, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent2×

Procedure

Following the procedure of Example 1, 2-[4-(1-methyl-n-butoxy)phenoxy]ethanol (0.80 g, 3.6 mmol) in 5 ml of DMF is added to sodium hydride (0.26 g, 5.3 mmol) in 5 ml of DMF, followed by addition of 2-chloropyridine (0.50 g, 5.3 mmol) to give 2-{2-[4-(1-methyl-n-butoxy)phenoxy]ethoxy}pyridine.

Sources & evidence

ORD record
ord-1d9ed152f8e74edeaf255bf9ceef2e87
Source dataset
uspto-grants-1995_02
Patent number
US05389651

Reaction notes

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