反应详情

To a solution of 10 g (75.1 mmol) of rhodanine and 7.63 ml (75.1 mmol) of benzaldehyde in 150 ml of ethanol, 0.74 ml (7.5 mmol) of piperidine was added, and the mixture was heated under reflux for 5 hours. After cooling, the precipitated crystals were filtered and washed with cooled ethanol to give 11.07 g of the desired compound (66.6% yield, pale yellow crystals).

1. temperaturethe mixture was heated
2. temperatureunder reflux for 5 hours
3. temperatureAfter cooling
4. filtrationthe precipitated crystals were filtered
5. washwashed with cooled ethanol