HCID 20089190, compound → HCID 20089209, compound

HRID 274931Notes

Reaction equation

HRID 274931 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([CH2:13][CH:14]=[CH2:15])[C:11]=1[OH:12])[C:5]([O:7][CH3:8])=[O:6].[H][H]>C(O)C.[Rh]>[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([CH2:13][CH2:14][CH3:15])[C:11]=1[OH:12])[C:5]([O:7][CH3:8])=[O:6]

Participants

5

Reactant 2

HCID 20089190HCID 20089190, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 20089209HCID 20089209, compound

Reagents, catalysts & solvents 2

HCID 23948RhodiumCatalystHCID 702EthanolSolvent

Procedure

A Parr flask was charged with a solution of 14.784 g (65.2 mmol) of the product of step A dissolved in 80 mL ethanol and 0.485 g of 5% rhodium on alumina catalyst was added. The reaction mixture was mounted in a Parr hydrogenation apparatus, pressurized to 40 psig hydrogen and shaken for 30 minutes. The reaction vessel was then removed from the apparatus, the contents were filtered and the flitrate was evaporated and dried in vacuo to afford 14.878 (99%) of the title compound.

Workup

  1. customThe reaction vessel was then removed from the apparatus
  2. filtrationthe contents were filtered
  3. customthe flitrate was evaporated
  4. customdried in vacuo

Sources & evidence

ORD record
ord-d7716e11934e4bbbbed614d533f129dc
Source dataset
uspto-grants-1995_02
Patent number
US05391566

Reaction notes

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