HCID 10496436, compound → HCID 10657146, compound

HRID 275322Notes

Reaction equation

HRID 275322 reaction equation
[CH3:1][N:2]1[C:10](=[O:11])[C:9]2[N:8](CC3C=CC=CC=3)[CH:7]=[N:6][C:5]=2[N:4]2[C@H:19]3[CH2:24][CH2:23][CH2:22][C@H:20]3[N:21]=[C:3]12>CCO.[OH-].[OH-].[Pd+2]>[CH3:1][N:2]1[C:10](=[O:11])[C:9]2[NH:8][CH:7]=[N:6][C:5]=2[N:4]2[C@H:19]3[CH2:24][CH2:23][CH2:22][C@H:20]3[N:21]=[C:3]12

Participants

4

Reactant 1

HCID 10496436HCID 10496436, compound

Product 1

HCID 10657146HCID 10657146, compound

Reagents, catalysts & solvents 2

HCID 9942167Palladium hydroxideCatalystHCID 702EthanolSolvent

Procedure

Hydrogenate cis-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylmethyl)cyclopenta[4,5]imidazo[2,1-b]purin-4-one (0.3 g=0.93 mmol) at room temperature/60 psi in EtOH (125 ml) containing 0.4 g Pearlman catalyst. Filter catalyst, remove solvent, and recrystallize to give the title compound as a white solid. FAB MS: M+1=232.

Workup

  1. customFilter catalyst, remove solvent
  2. customrecrystallize

Sources & evidence

ORD record
ord-429e256a0d5a48f59c480e1055754172
Source dataset
uspto-grants-1995_02
Patent number
US05393755

Reaction notes

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