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HRID27680

反应详情

EQUATION

反应方程式

HRID 27680 的结构方程式

REACTANTS

反应物

4
结构：NC=O
HCID713

Formamide

CH3NO

结构：CC(=O)OC(C)=O
HCID7918

Acetic anhydride

C4H6O3

结构：CCN(CC)c1ccc(N=Nc2c(Br)cc([N+](=O)[O-])cc2[N+](=O)[O-])c(NC(C)=O)c1
HCID104287

N-(2-((2-Bromo-4,6-dinitrophenyl)azo)-5-(diethylamino)phenyl)acetamide

C18H19BrN6O5

结构：CC(=O)[O-].[K+]
HCID517044

Potassium acetate

C2H3KO2

PRODUCTS

生成物

1
结构：CCN(CC)c1ccc(N=Nc2c(C#N)cc([N+](=O)[O-])cc2[N+](=O)[O-])c(NC(C)=O)c1
HCID90383

N-(2-((2-Cyano-4,6-dinitrophenyl)azo)-5-(diethylamino)phenyl)acetamide

C19H19N7O5

收率 95%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Cu][I]
催化剂HCID24350

Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

CuI

结构：CCCCOC(C)=O
溶剂HCID31272

Butyl acetate

C6H12O2

CONDITIONS

反应条件

温度
110 °C

PROCEDURE

实验过程

2-Bromo-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino) azobenzene (2.4 parts), copper (I) iodide (0.95 parts), anhydrous potassium acetate (1.5 parts), formamide (1.8 parts), acetic anhydride (2.0 parts) and n-butyl acetate (44 parts) are mixed together and heated, with stirring, to 110° C. during 15 minutes. The temperature is maintained at 110° C. for 2 hours when reaction is complete. The mixture is cooled to room temperature and poured into petroleum ether (boiling range 60-80° C.) (400 parts). The precipitate is collected, washed with petroleum ether (100 parts) and dried. 2-Cyano-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene is obtained in 95% yield.

WORKUP

后处理

  1. temperatureheated
  2. temperatureThe temperature is maintained at 110° C. for 2 hours
  3. customwhen reaction
  4. temperatureThe mixture is cooled to room temperature
  5. customThe precipitate is collected
  6. washwashed with petroleum ether (100 parts)
  7. customdried