Hydrochloric Acid → HCID 10979887, compound

HRID 277308Notes

Reaction equation

HRID 277308 reaction equation
C1C=C2C(C(O)(O)C(=O)C2=CC=1)=O.Cl.CO[C:17]1[CH:40]=[CH:39][C:20]([C:21]([NH:34][CH2:35][CH2:36][N+:37]#[C-:38])([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:19][CH:18]=1.COC1C=CC(C(NCC[N+]#[C-])(C2C=CC=CC=2)C2C=CC(OC)=CC=2)=CC=1>C(Cl)Cl.CO>[C:21]([NH:34][CH2:35][CH2:36][N+:37]#[C-:38])([C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[C:20]1[CH:39]=[CH:40][CH:17]=[CH:18][CH:19]=1

Participants

6

Reactant 4

HCID 313Hydrochloric Acid3×HCID 10236Ninhydrin3×HCID 18314370HCID 18314370, compoundHCID 18314373HCID 18314373, compound

Product 1

HCID 10979887HCID 10979887, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent3×

Procedure

C22H20N2 (312.42); RF=0.90 (DCM/MeOH 5:1, v/v); spot stains with ninhydrin spray or with HCl vapour); 2-(4-monomethoxytrityl)aminoethylisocyanide; C23H22N2O (342.44); RF=0.89 (DCM/MeOH 5:1, v/v); spot stains with ninhydrin spray or with HCl vapour); 2-(4,4′-dimethoxytrityl)aminoethylisocyanide; C24H24N2O2 (372.47); RF=0.95 (DCM/MeOH 5:1, v/v); spot stains with ninhydrin spray or with HCl vapour);

Sources & evidence

ORD record
ord-573235537b7141a8b9545d215cbff6f9
Source dataset
uspto-grants-2002_03
Patent number
US06355726B1

Reaction notes

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