Hydrochloric Acid → HCID 22627942, compound

HRID 278585Notes

Reaction equation

HRID 278585 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[S:11]([N:14]1[CH2:19][CH2:18][N:17]([C:20](=[O:34])[C:21]2[CH:26]=[CH:25][C:24]([CH2:27][N:28]3[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]3)=[CH:23][CH:22]=2)[CH2:16][CH2:15]1)(=[O:13])=[O:12].[ClH:35]>C(OCC)(=O)C>[ClH:35].[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[S:11]([N:14]1[CH2:15][CH2:16][N:17]([C:20](=[O:34])[C:21]2[CH:26]=[CH:25][C:24]([CH2:27][N:28]3[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]3)=[CH:23][CH:22]=2)[CH2:18][CH2:19]1)(=[O:13])=[O:12]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22627943HCID 22627943, compound

Product 1

HCID 22627942HCID 22627942, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To 1-(2-naphthalenesulfonyl)-4-(4-piperidinomethylbenzoyl)piperazine (350 mg) was added 4 N hydrochloric acid in ethyl acetate solution (5 ml) and the precipitated hydrochlorides were filtered to give the title compound (337 mg).

Workup

  1. filtrationthe precipitated hydrochlorides were filtered

Sources & evidence

ORD record
ord-25d13c4608b24bf6a75dcbcf79cd3fc3
Source dataset
uspto-grants-2002_03
Patent number
US06359134B1

Reaction notes

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