Hydrochloric Acid → HCID 22628213, compound

HRID 278586Notes

Reaction equation

HRID 278586 reaction equation
[N:1]1([CH2:6][C:7]2[CH:33]=[CH:32][C:10]([C:11]([N:13]3[CH2:18][CH2:17][N:16]([S:19]([C:22]4[CH:31]=[CH:30][C:29]5[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=5)[CH:23]=4)(=[O:21])=[O:20])[CH2:15][CH2:14]3)=[O:12])=[CH:9][CH:8]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[ClH:34]>C(OCC)(=O)C>[ClH:34].[N:1]1([CH2:6][C:7]2[CH:8]=[CH:9][C:10]([C:11]([N:13]3[CH2:18][CH2:17][N:16]([S:19]([C:22]4[CH:31]=[CH:30][C:29]5[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=5)[CH:23]=4)(=[O:21])=[O:20])[CH2:15][CH2:14]3)=[O:12])=[CH:32][CH:33]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22627996HCID 22627996, compound

Product 1

HCID 22628213HCID 22628213, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To 1-[4-(1H-imidazol-1-ylmethyl)benzoyl]-4-(2-naphthalenesulfonyl)piperazine (300 mg) was added 4 N hydrochloric acid in ethyl acetate solution (5 ml) and the precipitated hydrochlorides were filtered to give the title compound (299 mg).

Workup

  1. filtrationthe precipitated hydrochlorides were filtered

Sources & evidence

ORD record
ord-769bf39da31541018657ca95e8fa74e7
Source dataset
uspto-grants-2002_03
Patent number
US06359134B1

Reaction notes

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