Hydrochloric Acid → HCID 22627944, compound

HRID 278588Notes

Reaction equation

HRID 278588 reaction equation
[CH2:1]([CH2:8][NH:9][CH2:10][C:11]1[CH:37]=[CH:36][C:14]([C:15]([N:17]2[CH2:22][CH2:21][N:20]([S:23]([C:26]3[CH:35]=[CH:34][C:33]4[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=4)[CH:27]=3)(=[O:25])=[O:24])[CH2:19][CH2:18]2)=[O:16])=[CH:13][CH:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:38]>C(OCC)(=O)C>[ClH:38].[CH2:1]([CH2:8][NH:9][CH2:10][C:11]1[CH:12]=[CH:13][C:14]([C:15]([N:17]2[CH2:18][CH2:19][N:20]([S:23]([C:26]3[CH:35]=[CH:34][C:33]4[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=4)[CH:27]=3)(=[O:24])=[O:25])[CH2:21][CH2:22]2)=[O:16])=[CH:36][CH:37]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22627945HCID 22627945, compound

Product 1

HCID 22627944HCID 22627944, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To 1-(4-benzylmethylaminomethylbenzoyl)-4-(2-naphthalenesulfonyl)piperazine (358 mg) was added 4 N hydrochloric acid in ethyl acetate solution (5 ml), and the precipitated hydrochlorides were filtered to give the title compound (391 mg).

Workup

  1. filtrationthe precipitated hydrochlorides were filtered

Sources & evidence

ORD record
ord-9427156c271f4e88b8896f8ceffbdee9
Source dataset
uspto-grants-2002_03
Patent number
US06359134B1

Reaction notes

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