Hydrochloric Acid → HCID 22628079, compound

HRID 278592Notes

Reaction equation

HRID 278592 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([S:12]([N:15]1[CH2:20][CH2:19][N:18]([C:21](=[O:36])[C:22]3[CH:27]=[CH:26][C:25]([CH2:28][N:29]([CH:33]([CH3:35])[CH3:34])[CH:30]([CH3:32])[CH3:31])=[CH:24][CH:23]=3)[CH2:17][CH2:16]1)(=[O:14])=[O:13])[CH:6]=[CH:5]2.Cl>C(OCC)(=O)C>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([S:12]([N:15]1[CH2:16][CH2:17][N:18]([C:21](=[O:36])[C:22]3[CH:27]=[CH:26][C:25]([CH2:28][N:29]([CH:33]([CH3:35])[CH3:34])[CH:30]([CH3:31])[CH3:32])=[CH:24][CH:23]=3)[CH2:19][CH2:20]1)(=[O:13])=[O:14])[CH:6]=[CH:5]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22627973HCID 22627973, compound

Product 1

HCID 22628079HCID 22628079, compoundYield 192.2%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To 1-(6-chloronaphthalene-2-sulfonyl)-4-(4-diisopropylaminomethylbenzoyl)piperazine (110 mg) was added 4 N hydrochloric acid in ethyl acetate solution (5 ml), and the precipitated hydrochlorides were filtered to give the title compound (113 mg).

Workup

  1. filtrationthe precipitated hydrochlorides were filtered

Sources & evidence

ORD record
ord-d77cc699844e419d9eef41ecf3b9053c
Source dataset
uspto-grants-2002_03
Patent number
US06359134B1

Reaction notes

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