Nitromethane → HCID 178526916, compound

HRID 27877Notes

Reaction equation

HRID 27877 reaction equation
O.[CH:2]([C:4]1[CH:13]=[N+:12]([O-:14])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[O-:15])=[O:3].[N+:16]([CH3:19])([O-:18])=[O:17]>CO.C(N(CC)CC)C>[N+:16]([CH2:19][CH:2]([C:4]1[CH:13]=[N+:12]([O-:14])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[O-:15])[OH:3])([O-:18])=[O:17]

Participants

5

Reactant 2

HCID 6375NitromethaneHCID 1785269452-Formylquinoxaline-1,4-dioxide hydrate

Product 1

HCID 178526916HCID 178526916, compound

Reagents, catalysts & solvents 2

HCID 8471TriethylamineCatalystHCID 887MethanolSolvent

Procedure

2-Formylquinoxaline-1,4-dioxide hydrate, 2 g (0.01 mole) was dissolved in 100 ml of warm methanol. Ten drops of triethylamine were added with stirring and 1 g (0.016 mole) of nitromethane was added. The heat source was removed and the reaction mixture was allowed to cool to room temperature. The methanol was removed by evaporation and the residue was recrystallized from water. There was obtained 2-(2-nitro-1-hydroxyethyl)quinoxaline-1,4-dioxide. It was designated P-2231 for convenience.

Workup

  1. customThe heat source was removed
  2. customThe methanol was removed by evaporation
  3. customthe residue was recrystallized from water

Sources & evidence

ORD record
ord-a22ae5bf435d45b0a441e689225ded38
Source dataset
uspto-grants-1980_09
Patent number
US04224324

Reaction notes

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