HRID278952

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)[Si](C)(C)ON1C(=O)c2cccc3cc([N+](=O)[O-])cc(c23)C1=O

HCID131722278

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)[Si](C)(C)ON1C(=O)c2cccc3cc(N)cc(c23)C1=O

HCID131722280

未命名化合物

收率 86.5%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

The hydrogenation of 2-tert-butyldimethylsilyoxy-5-nitro-benzo[de]isoquinoline-1,3-dione (1.0 g, 2.7 mmol, from Example A-1 or A-2) at 40 psi in the presence of 10% Pd/C catalyst (1.0 g) in ethyl acetate (20 mL) afforded 0.8 g of the title compound.