反应详情

A mixture of 0.65 g (1.7 mmol) of methyl methoxyimino-[2-(1-(4-chlorophenyl)-3-pyrazolyloxy)pyridin-3-yl]acetate (Example 1.b) and 3.2 g of 40% strength aqueous methylamine solution in 2 ml of tetrahydrofuran were heated under reflux for 0.5 hours. The reaction mixture was freed from the solvent under reduced pressure. The residue was stirred with pentane/water, and the solid was separated off, washed with water and dried under reduced pressure. 0.55 g (84%) of the title compound was obtained as a white solid.

1. temperaturewere heated
2. temperatureunder reflux for 0.5 hours
3. customthe solid was separated off
4. washwashed with water
5. customdried under reduced pressure