Benzyl Chloride → HCID 22624572, compound

HRID 279154Notes

Reaction equation

HRID 279154 reaction equation
[C:1]([CH:4]1[CH2:13][CH2:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]1=[O:14])(=[O:3])[CH3:2].C(=O)([O-])[O-].[K+].[K+].[CH2:21](Cl)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>C(#N)C>[C:1]([C:4]1([CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:13][CH2:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]1=[O:14])(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 7503Benzyl ChlorideHCID 11430Potassium CarbonateHCID 865272-Acetyl-1,2,3,4-tetrahydronaphthalen-1-one

Product 1

HCID 22624572HCID 22624572, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Conditions

Temperature
60 °C

Procedure

2-Acetyl-1-tetralone (5.0 g) was added into a mixture of potassium carbonate (3.8 g) and acetonitrile (60 ml). The mixture was stirred at 60° C. for 30 minutes and benzyl chloride was added and the stirring was continued at 60° C. for 5 hours. The mixture was filtered and evaporated. The yield was 7.2 g and was used for further reactions without purification.

Workup

  1. waitthe stirring was continued at 60° C. for 5 hours
  2. filtrationThe mixture was filtered
  3. customevaporated
  4. customThe yield was 7.2 g and was used for further reactions without purification

Sources & evidence

ORD record
ord-f5750697163747a6a3582cd8357d6ae5
Source dataset
uspto-grants-2002_03
Patent number
US06362211B1

Reaction notes

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