Hydrochloric Acid → HCID 23322753, compound

HRID 279843Notes

Reaction equation

HRID 279843 reaction equation
[C:1]([O:5][C:6]([CH2:8][N:9]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH:11]([NH:18][CH:19]([C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH2:20][CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:10]1=[O:33])=[O:7])(C)(C)[CH3:2].Cl>C(O)C>[CH2:1]([O:5][C:6]([CH2:8][N:9]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH:11]([NH:18][CH:19]([C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH2:20][CH2:21][C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)[C:10]1=[O:33])=[O:7])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13608329HCID 13608329, compound

Product 1

HCID 23322753HCID 23322753, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1-t-Butoxycarbonylmethyl-3-(1-ethoxycarbonyl-3-phenylpropyl)aminoperhydroazonin-2-one (Example 1) is treated with hydrogen chloride in ethanol followed by concentration and partitioning of the residue between aqueous potassium carbonate and ethyl acetate. Drying and concentration of the organic phase affords the title product.

Workup

  1. concentrationfollowed by concentration
  2. custompartitioning of the residue between aqueous potassium carbonate and ethyl acetate
  3. customDrying

Sources & evidence

ORD record
ord-dbb232061da342318ef430f1d58cf0a4
Source dataset
uspto-grants-1986_05
Patent number
US04587238

Reaction notes

Loading…