Hydrochloric Acid → HCID 12461092, compound

HRID 280369Notes

Reaction equation

HRID 280369 reaction equation
[S:1]([O:5][CH2:6][CH:7]1[O:9][CH2:8]1)([CH3:4])(=[O:3])=[O:2].[ClH:10]>>[S:1]([O:5][CH2:6][CH:7]([OH:9])[CH2:8][Cl:10])([CH3:4])(=[O:3])=[O:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 110799(Oxiran-2-yl)methyl methanesulfonate

Product 1

HCID 12461092HCID 12461092, compoundYield 85%

Procedure

Concentrated HCl (20 ml) was added to 3-mesyloxy-1,2-epoxypropane (5.0 g, 0.033 m) over 15-20 minutes. After stirring for an additional 30 minutes, the water was removed through the addition and subsequent evaporation of ethanol. Finally, residual ethanol was removed at room temperature and 0.1 mm to give 3-mesyloxy-2-hydroxy-1-chloropropane (5.4 g, 85%).

Workup

  1. customthe water was removed through the addition and subsequent evaporation of ethanol
  2. customFinally, residual ethanol was removed at room temperature

Sources & evidence

ORD record
ord-09c6936c4bc24d39a6df3b5fb0066b2c
Source dataset
uspto-grants-1986_05
Patent number
US04588824

Reaction notes

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