N,N-Diethylaniline → HCID 70507608, compound

HRID 280546Notes

Reaction equation

HRID 280546 reaction equation
ClC1C=C[C:5]([C:6](C2C=C(C=CN=2)C(NC2C=CC=CC=2)=O)=[O:7])=CC=1.[Cl:25][C:26]1([CH:40]=[CH:39][N:38]=[C:37]([C:41](=[O:48])[C:42]2[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=2)[CH2:36]1)[C:27]([NH:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)=[O:28].[CH2:49](N(CC)C1C=CC=CC=1)[CH3:50]>C(N(CC)CC)C>[CH2:49]([O:28][C:27]([O:7][CH2:6][CH3:5])([NH:29][C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=1)[C:26]1([Cl:25])[CH:40]=[CH:39][N:38]=[C:37]([C:41](=[O:48])[C:42]2[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=2)[CH2:36]1)[CH3:50]

Participants

5

Reactant 3

HCID 7061N,N-DiethylanilineHCID 13562483HCID 13562483, compoundHCID 70457375HCID 70457375, compound

Product 1

HCID 70507608HCID 70507608, compoundYield 75%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The procedure of Synthesis 1 was repeated except that 2-(4-chlorobenzoyl)-isonicotinanilide and triethylamine was replaced by 4-chloro-2-benzoyl-isonicotinanilide (11.2 g) and N,N-diethylaniline (15 ml), respectively. The titled compound was obtained in an amount of 10.3 g (yield: 75%). m.p. 133°-134° C.

Workup

  1. customThe procedure of Synthesis 1

Sources & evidence

ORD record
ord-d7ed0b58dcac49c6b9a0939e2c8aaa3a
Source dataset
uspto-grants-1986_05
Patent number
US04590198

Reaction notes

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