5-((Dimethylamino)methyl)-2-furanmethanol → HCID 70515975, compound

HRID 280559Notes

Reaction equation

HRID 280559 reaction equation
[SH:1][CH2:2][CH2:3][C:4]1[C:15]([NH2:16])=[C:8]2[C:9]([NH2:14])=[N:10][S:11](=[O:13])(=[O:12])[C:7]2=[CH:6][CH:5]=1.[CH3:17][N:18]([CH2:20][C:21]1[O:25][C:24]([CH2:26]O)=[CH:23][CH:22]=1)[CH3:19]>Cl>[CH3:17][N:18]([CH2:20][C:21]1[O:25][C:24]([CH2:26][S:1][CH2:2][CH2:3][C:4]2[C:15]([NH2:16])=[C:8]3[C:9]([NH2:14])=[N:10][S:11](=[O:13])(=[O:12])[C:7]3=[CH:6][CH:5]=2)=[CH:23][CH:22]=1)[CH3:19]

Participants

4

Reactant 2

HCID 849065-((Dimethylamino)methyl)-2-furanmethanolHCID 86740812HCID 86740812, compound

Product 1

HCID 70515975HCID 70515975, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

To a stirred solution of N3 -[2-mercapto ethyl]-1,2-benzoisothiazole-3,4-diamine-1,1-dioxide (D.9, 0.11 g) in concentrated hydrochloric acid (0.4 ml) under nitrogen at -10° C. was added 5-dimethylaminomethyl-2-furanmethanol (0.08 g). After stirring at room temperature overnight, the reaction mixture was worked-up as described in Example 2 to afford the title compound.

Sources & evidence

ORD record
ord-0a31c9ba02ca448eaa59399e126bb409
Source dataset
uspto-grants-1986_05
Patent number
US04590192

Reaction notes

Loading…