反应详情

4.5 g (0.02 moles) of carnitine hydrochloride were dissolved in 6 ml of trifluoroacetic acid. To this solution 4-methoxybutyryl chloride was added. The resulting mixture was kept under stirring at room temperature for 16 days. Subsequently tert-butyl methyl ether was added to the mixture. An oil precipitated which was treated with anhydrous acetonitrile in order to remove the undesired carnitine. To the acetonitrile solution tert-butyl methyl ether was added and 4-methoxybutyryl carnitine precipitated. Yield 50%.

1. customAn oil precipitated which
2. additionwas treated with anhydrous acetonitrile in order
3. customto remove the undesired carnitine
4. additionTo the acetonitrile solution tert-butyl methyl ether was added
5. custom4-methoxybutyryl carnitine precipitated