Tetrahydrofuran → 2-(3,4-Dichlorophenyl)-4-(t-butyldimethylsilyloxy)butyronitrile
Reaction equation
[C:22]([CH3:23])([CH3:24])([CH3:25])[Si:26]([O:27][CH2:28][CH2:29][Br:30])([CH3:31])[CH3:32].[CH3:12][Si:13]([N-:14][Si:15]([CH3:16])([CH3:17])[CH3:18])([CH3:19])[CH3:20].[Cl:1][c:2]1[cH:3][c:4]([CH2:9][C:10]#[N:11])[cH:5][cH:6][c:7]1[Cl:8].[Li+:21].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[Cl:1][c:2]1[cH:3][c:4]([CH:9]([C:10]#[N:11])[CH2:29][CH2:28][O:27][Si:26]([C:22]([CH3:23])([CH3:24])[CH3:25])([CH3:31])[CH3:32])[cH:5][cH:6][c:7]1[Cl:8]Participants
6
Sources & evidence
- ORD record
- ord-f7807c43d6824eeabb848e017aa7d3b9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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