Dimethylformamide → 4-{[4-(5-fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carbonyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:42]([CH3:43])([CH3:44])([CH3:45])[O:46][C:47](=[O:48])[NH:49][CH:50]1[CH2:51][CH2:52][NH:53][CH2:54][CH2:55]1.[CH3:94][CH2:95][O:96][C:97](=[O:98])[CH3:99].[CH:1]1([CH2:11][N:12]2[CH2:13][CH2:14][CH:15]([NH:18][C:19](=[O:20])[c:21]3[nH:22][c:23]4[cH:24][cH:25][cH:26][c:27]([O:30][CH2:31][c:32]5[cH:33][o:34][c:35]6[c:36]5[cH:37][c:38]([F:41])[cH:39][cH:40]6)[c:28]4[cH:29]3)[CH2:16][CH2:17]2)[CH:2]2[N:3]([CH2:4][CH2:5][CH2:6][CH2:7]2)[CH2:8][CH2:9][CH2:10]1.[O:89]=[CH:90][N:91]([CH3:92])[CH3:93].[P-:56]([F:57])([F:58])([F:59])([F:60])([F:61])[F:62].[n:63]1([O:72][P+:64]([N:65]2[CH2:66][CH2:67][CH2:68][CH2:69]2)([N:70]2[CH2:71][CH2:73][CH2:74][CH2:75]2)[N:76]2[CH2:77][CH2:78][CH2:79][CH2:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][c:86]2[n:87][n:88]1>>[C:11]([N:12]1[CH2:13][CH2:14][CH:15]([NH:18][C:19](=[O:20])[c:21]2[nH:22][c:23]3[cH:24][cH:25][cH:26][c:27]([O:30][CH2:31][c:32]4[cH:33][o:34][c:35]5[c:36]4[cH:37][c:38]([F:41])[cH:39][cH:40]5)[c:28]3[cH:29]2)[CH2:16][CH2:17]1)([O:46][C:42]([CH3:43])([CH3:44])[CH3:45])=[O:72]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f06593c2242c4dde938cec0d8fa7f7b8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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