Dichloromethane → benzyl N-[4-[[[2-[2,6-difluoro-4-(2-morpholin-4-ylethoxy)phenyl]-2-ethoxyacetyl]amino]methyl]benzenecarboximidoyl]carbamate
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([NH:10][C:11](=[NH:12])[c:13]1[cH:14][cH:15][c:16]([CH2:19][NH:20][C:21]([CH:22]([O:23][CH2:24][CH3:25])[c:26]2[c:27]([F:34])[cH:28][c:29]([OH:33])[cH:30][c:31]2[F:32])=[O:35])[cH:17][cH:18]1)=[O:36].[Cl:81][CH2:82][Cl:83].[N:65]([C:66]([O:67][C:68]([CH3:69])([CH3:70])[CH3:71])=[O:72])=[N:73][C:74]([O:75][C:76]([CH3:77])([CH3:78])[CH3:79])=[O:80].[OH:37][CH2:38][CH2:39][N:40]1[CH2:41][CH2:42][O:43][CH2:44][CH2:45]1.[c:46]1([P:47]([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[cH:60][cH:61][cH:62][cH:63][cH:64]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([NH:10][C:11](=[NH:12])[c:13]1[cH:14][cH:15][c:16]([CH2:19][NH:20][C:21]([CH:22]([O:23][CH2:24][CH3:25])[c:26]2[c:27]([F:34])[cH:28][c:29]([O:33][CH2:38][CH2:39][N:40]3[CH2:41][CH2:42][O:43][CH2:44][CH2:45]3)[cH:30][c:31]2[F:32])=[O:35])[cH:17][cH:18]1)=[O:36]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8c3efaa028c74112a4e9d642f113dd5d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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