Tetrahydrofuran → (5-Chloromethyl-quinolin-2-yl)-(5-methyl-furan-2-ylmethyl)-amine

HRID 282038Notes

Reaction equation

HRID 282038 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([CH2:7][NH:8][c:9]2[n:10][c:11]3[cH:12][cH:13][cH:14][c:15]([CH2:19][OH:20])[c:16]3[cH:17][cH:18]2)[o:6]1.[CH3:21][S:22]([Cl:23])(=[O:24])=[O:25].[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5]([CH2:7][NH:8][c:9]2[n:10][c:11]3[cH:12][cH:13][cH:14][c:15]([CH2:19][Cl:23])[c:16]3[cH:17][cH:18]2)[o:6]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 31297Methanesulfonyl chlorideHCID 81531DiisopropylethylamineHCID 44218152{2-[(5-Methyl-furan-2-ylmethyl)-amino]-quinolin-5-yl}-methanol

Product 1

HCID 68436366(5-Chloromethyl-quinolin-2-yl)-(5-methyl-furan-2-ylmethyl)-amine

Sources & evidence

ORD record
ord-00a88aaeb8e247cf9c1ffdb925d8f6b5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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