Dichloromethane → 4-O-benzyl 1-O-tert-butyl 3-O-methyl piperidine-1,3,4-tricarboxylate

HRID 282190Notes

Reaction equation

HRID 282190 reaction equation
[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[Cl:26][C:27](=[O:28])[O:29][CH2:30][c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1.[Cl:37][CH2:38][Cl:39].[NH2:1][CH:2]1[CH:3]([C:15](=[O:16])[O:17][CH3:18])[CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1>>[CH:2]1([C:27](=[O:28])[O:29][CH2:30][c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH:3]([C:15](=[O:16])[O:17][CH3:18])[CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 10387Benzyl chloroformateHCID 592166281-O-tert-butyl 3-O-methyl 4-aminopiperidine-1,3-dicarboxylate

Product 1

HCID 218742134-O-benzyl 1-O-tert-butyl 3-O-methyl piperidine-1,3,4-tricarboxylate

Sources & evidence

ORD record
ord-4e2720a9b6934240beeb63c59095bf5e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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