Water → Ethyl 4-{5-[(3,5-bis-trifluoromethyl-benzyl)-(5'-isopropyl-2'-methoxy-4-trifluoromethyl-biphenyl-2-ylmethyl)-amino]-tetrazol-2-yl}-butyrate
Reaction equation
[Br:51][CH2:52][CH2:53][CH2:54][C:55](=[O:56])[O:57][CH2:58][CH3:59].[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[CH3:61][N:62]([CH3:63])[CH:64]=[O:65].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([c:8]2[n:9][n:10][nH:11][n:12]2)[CH2:13][c:14]2[c:15](-[c:24]3[c:25]([O:33][CH3:34])[cH:26][cH:27][c:28]([CH:30]([CH3:31])[CH3:32])[cH:29]3)[cH:16][cH:17][c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[cH:35][c:36]([C:38]([F:39])([F:40])[F:41])[cH:37]1)([F:42])[F:43].[OH2:60]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([c:8]2[n:9][n:10][n:11]([CH2:52][CH2:53][CH2:54][C:55](=[O:56])[O:57][CH2:58][CH3:59])[n:12]2)[CH2:13][c:14]2[c:15](-[c:24]3[c:25]([O:33][CH3:34])[cH:26][cH:27][c:28]([CH:30]([CH3:31])[CH3:32])[cH:29]3)[cH:16][cH:17][c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[cH:35][c:36]([C:38]([F:39])([F:40])[F:41])[cH:37]1)([F:42])[F:43]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-77fcefa9d0394109be03be36d9e075ad
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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