Hydroxyamine hydrochloride → HCID 13051039, compound

HRID 28240Notes

Reaction equation

HRID 28240 reaction equation
C(O)(=O)C.[OH:5][C:6]1[CH:19]=[C:18]2[C:9]([CH:10]=[CH:11][C:12]3[O:13][CH:14]=[C:15]([CH:21]=O)[C:16](=[O:20])[C:17]=32)=[CH:8][CH:7]=1.Cl.[NH2:24]O.C([O-])=O.[Na+]>C(O)=O>[OH:5][C:6]1[CH:19]=[C:18]2[C:9]([CH:10]=[CH:11][C:12]3[O:13][CH:14]=[C:15]([C:21]#[N:24])[C:16](=[O:20])[C:17]=32)=[CH:8][CH:7]=1

Participants

5

Reactant 3

HCID 443297Hydroxyamine hydrochlorideHCID 2723810Sodium FormateHCID 867372399-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carboxaldehyde acetate

Product 1

HCID 13051039HCID 13051039, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

A mixture of 9-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carboxaldehyde acetate (1 mm), hydroxylamine hydrochloride (1.3 mm) and sodium formate (2 mm) is refluxed for 30 hrs. in formic acid (3 parts). The product crystallize on cooling, is filtered and washed with acetone. The dry crystals are light beige, m.p. 289°-92° C.

Workup

  1. temperatureis refluxed for 30 hrs
  2. customThe product crystallize
  3. temperatureon cooling
  4. filtrationis filtered
  5. washwashed with acetone

Sources & evidence

ORD record
ord-1f75bfc4a18549a383df5e6ba879eded
Source dataset
uspto-grants-1980_09
Patent number
US04225722

Reaction notes

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