Dimethylacetamide → 4-(4-Methylpiperazin-1-yl)-3-(trifluoromethyl)benzonitrile
Reaction equation
[Br:1][c:2]1[c:3]([C:10]([F:11])([F:12])[F:13])[cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1.[CH3:14][N:15]1[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]1.[CH3:21][N:22]([CH3:23])[C:24](=[O:25])[CH3:26]>>[c:2]1([N:18]2[CH2:17][CH2:16][N:15]([CH3:14])[CH2:20][CH2:19]2)[c:3]([C:10]([F:11])([F:12])[F:13])[cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1Participants
4
Sources & evidence
- ORD record
- ord-ee3737b884cf4f0b956ea606c9eb5b62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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