Chloride → 2-[p-(2,2-Dichlorocyclopropylcarbonylamino)-phenyl]-3,4-diaza-bicyclo[4.1.0]hept-2-en-5-one

HRID 282581Notes

Reaction equation

HRID 282581 reaction equation
[Cl-:16].[Cl:17][C:18]1([Cl:24])[CH:19]([C:21](=[O:22])[OH:23])[CH2:20]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:14][NH:13][C:12](=[O:15])[CH:11]3[CH:9]2[CH2:10]3)[cH:6][cH:7]1.[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:14][NH:13][C:12](=[O:15])[CH:11]3[CH:9]2[CH2:10]3)[cH:6][cH:7]1)[C:21]([CH:19]1[C:18]([Cl:17])([Cl:24])[CH2:20]1)=[O:22]

Participants

5

Reactant 4

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 27949752,2-Dichlorocyclopropane-1-carboxylic acidHCID 202648445-(4-Aminophenyl)-3,4-diazabicyclo[4.1.0]hept-4-en-2-one

Product 1

HCID 234584932-[p-(2,2-Dichlorocyclopropylcarbonylamino)-phenyl]-3,4-diaza-bicyclo[4.1.0]hept-2-en-5-one

Sources & evidence

ORD record
ord-60f2e7ba26294766b50dc623c1ddffcf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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