Dichloromethane → 3-(5-Fluoro-2-hydroxyphenyl)-1-pentylindolin-2-one

HRID 282939Notes

Reaction equation

HRID 282939 reaction equation
[CH2:32]([SiH:33]([CH2:34][CH3:35])[CH2:36][CH3:37])[CH3:38].[Cl:39][CH2:40][Cl:41].[F:1][c:2]1[cH:3][cH:4][c:5]([OH:24])[c:6]([C:8]2([OH:23])[C:9](=[O:22])[N:10]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]32)[cH:7]1.[OH:25][C:26]([C:27]([F:28])([F:29])[F:30])=[O:31]>>[F:1][c:2]1[cH:3][cH:4][c:5]([OH:24])[c:6]([CH:8]2[C:9](=[O:22])[N:10]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]32)[cH:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 120043043-(5-fluoro-2-hydroxyphenyl)-3-hydroxy-1-pentyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 588724603-(5-Fluoro-2-hydroxyphenyl)-1-pentylindolin-2-one

Sources & evidence

ORD record
ord-53e1a95669eb496a9effb6ac0c2c70ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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