Diethyl Ether → tert-butyl N-[4-(butylamino)-3-hydroxy-1-phenylbutan-2-yl]carbamate

HRID 283251Notes

Reaction equation

HRID 283251 reaction equation
[Br:21][CH2:22][CH2:23][CH2:24][CH3:25].[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[NH:8][CH:9]([CH:10]([CH2:11][NH2:12])[OH:13])[CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1.[CH2:26]([O:27][CH2:28][CH3:29])[CH3:30].[CH3:31][N:32]([CH3:33])[CH:34]=[O:35]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[NH:8][CH:9]([CH:10]([CH2:11][NH:12][CH2:22][CH2:23][CH2:24][CH3:25])[OH:13])[CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 6228DimethylformamideHCID 8002Butyl bromideHCID 11065838tert-butyl N-(4-amino-3-hydroxy-1-phenylbutan-2-yl)carbamate

Product 1

HCID 70183766tert-butyl N-[4-(butylamino)-3-hydroxy-1-phenylbutan-2-yl]carbamate

Sources & evidence

ORD record
ord-f4c3cce4c05e4d2fa390947bd2af48cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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