Hydrochloric Acid → N-[(2-bromo-4-chlorophenyl)methyl]-1-(6-fluoro-3-pyridinyl)pyrrolidin-3-amine
Reaction equation
[BH4-:32].[Br:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][c:8]([Cl:10])[cH:9]1.[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:34][OH:35].[ClH:11].[F:12][c:13]1[cH:14][cH:15][c:16]([N:19]2[CH2:20][CH:21]([NH2:24])[CH2:22][CH2:23]2)[cH:17][n:18]1.[Na+:33]>>[Br:1][c:2]1[c:3]([CH2:4][NH:24][CH:21]2[CH2:20][N:19]([c:16]3[cH:15][cH:14][c:13]([F:12])[n:18][cH:17]3)[CH2:23][CH2:22]2)[cH:6][cH:7][c:8]([Cl:10])[cH:9]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d6c44b0d20f9438a8dfb7a2aac9a706b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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