N-methyl-2-pyrrolidone → tert-Butyl 4-[(5-bromopyridin-2-yl)amino]piperidine-1-carboxylate
Reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1.[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][CH:19]([NH2:22])[CH2:20][CH2:21]1.[CH3:32][N:33]1[CH2:34][CH2:35][CH2:36][C:37]1=[O:38].[CH:23]([N:24]([CH:25]([CH3:26])[CH3:27])[CH2:28][CH3:29])([CH3:30])[CH3:31]>>[c:2]1([NH:22][CH:19]2[CH2:18][CH2:17][N:16]([C:14]([O:13][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:15])[CH2:21][CH2:20]2)[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-dace14369fbc41f98e2b3b7199bd895a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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