Hydrochloric Acid → (2-Bromo-pyridin-4-yl)-[5-(4-dimethylamino-piperidin-1-yl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzoimidazol-2-yl]-methanone
Reaction equation
[Br:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8](=[O:9])[c:10]2[n:11][c:12]3[c:13]([nH:14]2)[cH:15][cH:16][c:17]([N:19]2[CH2:20][CH2:21][CH:22]([N:25]([CH3:26])[CH3:27])[CH2:23][CH2:24]2)[cH:18]3)[cH:7]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:30][Si:31]([CH2:32][CH2:33][O:34][CH2:35][Cl:36])([CH3:37])[CH3:38].[ClH:39].[H-:29].[Na+:28]>>[Br:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8](=[O:9])[c:10]2[n:11][c:12]3[c:13]([n:14]2[CH2:35][O:34][CH2:33][CH2:32][Si:31]([CH3:30])([CH3:37])[CH3:38])[cH:15][cH:16][c:17]([N:19]2[CH2:20][CH2:21][CH:22]([N:25]([CH3:26])[CH3:27])[CH2:23][CH2:24]2)[cH:18]3)[cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-78e198cac55442cc97df7bd24c806713
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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