Sodium ion → Tert-butyl 6-(4-chlorophenyl)-1-methyl-7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate

HRID 285271Notes

Reaction equation

HRID 285271 reaction equation
[CH2:39]([Cl:40])[Cl:41].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[C:9]([CH3:21])[CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[Na+:37].[Na+:38].[OH:22][O:23][C:24]([c:25]1[cH:26][c:27]([Cl:28])[cH:29][cH:30][cH:31]1)=[O:32].[S:33]([O-:34])([O-:35])=[O:36]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]23[C:9]([CH3:21])([CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[O:22]3)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 1099SulfiteHCID 6344DichloromethaneHCID 70297m-Chloroperbenzoic acidHCID 59444194Tert-butyl 4-(4-chlorophenyl)-3-methyl-5,6-dihydropyridine-1(2H)-carboxylate

Product 1

HCID 59444250Tert-butyl 6-(4-chlorophenyl)-1-methyl-7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate

Sources & evidence

ORD record
ord-7e560633a78b40f38399691f5349fdce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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