Bromide ion → 1-Tert-butyl-2-methoxy-5-(trifluoromethyl)-4-nitrobenzene

HRID 285741Notes

Reaction equation

HRID 285741 reaction equation
[Br-:19].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[c:6]([O:15][CH3:16])[cH:7][c:8]([N+:12](=[O:13])[O-:14])[c:9]([Br:11])[cH:10]1.[Cl:21][C:22]([C:23]([O:24][CH3:25])=[O:26])([F:27])[F:28].[Cu:35][I:36].[F-:17].[K+:18].[K+:20].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33].[OH2:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[c:6]([O:15][CH3:16])[cH:7][c:8]([N+:12](=[O:13])[O-:14])[c:9]([C:22]([F:17])([F:27])[F:28])[cH:10]1

Participants

9

Reactant 8

HCID 259Bromide ionHCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 28179Fluoride IonHCID 73935Methyl chlorodifluoroacetateHCID 574702451-Bromo-5-(tert-butyl)-4-methoxy-2-nitrobenzene

Product 1

HCID 574702461-Tert-butyl-2-methoxy-5-(trifluoromethyl)-4-nitrobenzene

Sources & evidence

ORD record
ord-064ed29561614a1ab97b37eaab8e9b36
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…